पूरक और वैकल्पिक चिकित्सा पद्दतियों और पशु होम्योपैथिक चिकित्सा के पहले डॆटाबेस का शुभारंभ (Launch of CAM Quest Database & Homeopathic Veterinary Database (VetCR))

Wednesday, 23 March 2011

जर्मनी में हाल ही में Carstens फाउंडेशन ने सीएएम में एक उत्कृष्ट क्लीकिल रिसर्च का ऑनलाइन डेटाबेस शुरू किया है. एक्यूपंक्चर, anthroposophic चिकित्सा, आयुर्वेद, bioenergetics, हर्बल चिकित्सा, होम्योपैथी, मैनुअल चिकित्सा, मन शरीर चिकित्सा और TCM: नौ विभिन्न उपचारोंको को इस अध्ययन मे शामिल किया गया है.
इस डेटाबेस मे जर्मनी  मे होम्योपैथिक केसों की रिपोर्ट की एक बड़ी संख्या शामिल है .वर्तमान में  यह डेटाबेस अंग्रेजी और फ्रेंच में उपलब्ध है,  लेकिन आगे  अन्य यूरोपीय भाषाओं में अनुवाद करने की योजना है.  इस साइट पर जाने के लिये  http://www.cam-quest.org  पर किल्क करें .
पहला होम्योपैथिक पशु चिकित्सा डेटाबेस (VetCR)
पशु चिकित्सा होम्योपैथी के मामले में नैदानिक ​​अनुसंधान के पहले डेटाबेस अब ऑनलाइन उपलब्ध है. मूल पशु चिकित्सा के अध्ययन पर सभी उपलब्ध साहित्य , यादृच्छिक चिकित्सीय परीक्षण, गैर यादृच्छिक चिकित्सीय परीक्षण, पर्यवेक्षणीय अध्ययन, औषधि की प्रूविगं इस साईट पर सुलभता से उपलब्ध है . इस साईट पर जाने के लिये http://www.carstens-stiftung.de/clinresvet/index.php प्रर किल्क करें .

Launch of CAM-QuestDatabase
The Carstens Foundation in Germany has recently launched an excellent online database of clinica lresearch in CAM. Studies in nine different therapies have been included: acupuncture, anthroposophic medicine, ayurveda, bioenergetics, herbal medicine, homeopathy, manual medicine, mind-body medicine and TCM.
The database includes a large number of German homeopathic case reports and provides the facility to perform searches by disease, therapy and study design. The ‘quick search’ function provides a synopsis of studies using the most common therapies for the most common diseases whilst the ‘expert search’ function enables a detailed, comprehensive search across the CAM therapies and full range of diseases within the database.
At present the database is available in English, French, Dutch and German, but there are plans to translate it into all European languages. It is accessible free of charge at  http://www.cam-quest.org
First Homeopathic Veterinary Database (VetCR)
The first database of clinical research in veterinary homeopathy is now accessible online. Containing all available literature on original veterinary studies it provides access to approximately 200 entries of randomised clinical trials, non-randomised clinical trials, observational studies, drug provings, case reports and case series.
Produced by the Carstens Foundation, the database is freely available at [ http://www.carstens-stiftung.de/clinresvet/index.php

स्वाइन फ़्लू , इन्फ़्लून्जियम और अन्य होम्योपैथिक औषधियाँ

Saturday, 22 August 2009

मिनेटेस डाट काम पर शेरी ने इन्फ़्लून्जियम पर कुछ रोचक आँकडॆ दिये ।  1918 से 1957 तक इस औषधि के स्त्रोत फ़्लू से ग्रस्त रोगियों के नासिक स्त्राव और  रक्त के सैम्पल से लिये गये । और  इनमे से अधिकतर उन रोगियों से जो 1918 के फ़्लू की महामारी से ग्रस्त थे ।

1957 के बाद से दवा बनाने के  ढंग  मे बदलाव आया और दवा का स्त्रोत फ़्लू वैक्सीन से लिया गया । इग्लैंड की नेलसन होम्यो लैब इसकी मुख्य निर्माता और विक्रेता हैं और 1918 से 1957  अब तक लगभग 13 अलग –2 सैम्पल ला चुके हैं । इनमे से अधिकतर सैम्पल इसके पूर्व वर्ष मे हुये फ़्लू के वैक्सीन  से लिये गये हैं । 1918 का फ़्लू वाइरस मुख्यत: H1N1 वाइरस था और यह अब तक के सबसे अधिक खतरनाक वाइरस की श्रेणी मे आता है । होम्योपैथिक दृष्टिकोण से मुख्य है इसकी प्रूविग जिससे उत्पन्न लक्षण लगभग वही थे जो फ़्लू के लक्षण से मेल खाते थे । नेलसन द्वारा  उत्पादित इन्फ़्लून्जियम के अन्य उत्पाद निम्म हैं :

1. *Influenzinum (the 1918 epidemic) *
1. 2. Influenza virus A Asia /57
1. 3. Influenza virus A England 42/72
1. 4. Influenza virus B Hong Kong 5/72
1. 5. Influenza virus A/Port Chalmers 1/73
1. 6. Influenza virus A (Asian) 1954
1. 7. Influenza virus B (Asian) 1954
1. 8. Bacillus influenza 1918
1. 9. Influenza virus Az Hong Kong 1968
1. 10. Influenza virus Ar 1967
1. 11. Influenza virus B
1. 12. Influenza Co. (Combination of Az to 1918)
1. 13. Influenza virus a1.

नेलसन लैब के एम्सवर्थ ने इन उत्पादन पर अपनी कुछ इस तरह टिप्पणी की ,

"Our 'Influenzinum' is a nosode but it is old. pre 1985.
All the others are made from vaccines except 1989 and triple nosode.
As the flu strains vary from year to year we make up fresh potencies
from the years 'most lightly flu's' vaccine each year in October".

लेकिन अपने देश मे कौन सा उत्पाद प्रयोग हो रहा है , इसके बारे मे दो प्रमुख कम्पनियाँ , बोइरोन इन्डिया और  श्वाबे इन्डिया ने भी अब तक कुछ खास जानकारी नही दी है ।

फ़्लू /स्वाइन /बर्ड /या आम फ़्लू से बचने के लिये इन्फ़्लूनिजियम प्रयोग करने का सही तरीका क्या है :

होम्योपैथिक दृष्टिकोण से  कोई फ़र्क नही पडता कि वह कौन सा फ़्लू है , स्वाइन / बर्ड / या आम फ़्लू , मुख्य है फ़्लू के लक्षणॊ का औषधि से मेल खाना  ।

इन्फ़्लूनिजियम नोसोड श्रेणी मे आता है और इसका व्यवहार भी  सावधानीपूर्वक करना चाहिये । इन्फ़्लूनिजियम 200 सपताह मे एक बार चार सप्ताह तक लगातार और इसके बाद महीने मे एक बार लें।

Influenzinum 200 c - take one dose every week for four weeks, and then, take the last dose one month later. This is intended as a strengthening/preventative measure

फ़्लू के लक्षण प्रकट होते ही किन औषधियों का प्रयोग करें :

  • ओसिलोकोकिनम या ऐनस बार्ब 200c : फ़्लू की शुरुआत होते ही इसका प्रयोग करें । फ़िलहाल अपने देश मे उपलब्धता  नही के बराबर है ।

Oscillococcinum aka Anas Barb 200c. There are two names for this remedy. It's Anas Barb in Nelsons. This is to be taken on the first onset of 'flu symptoms. It should catch the early onset of the 'flu. Though it’s not availbale in India .

  • चुनी हुई सही चयनित औषधि : होम्योपैथिक औषधि प्रयोग करने का यह तरीका सबसे कारगर और सही है । फ़्लू हो जाने पर सही चयनित औषधि का चयन किसी कुशल होम्योपैथिक चिकित्सक से करवायें और प्रयोग करें । इससे संबधित इस लेख को भी देखें ।

The Indicated Remedy if you actually get the full blown 'flu, then give the indicated 'flu remedy according to the symptoms. Here's a good guide: http://www.hpathy.com/diseases/Swine-flu-symptoms-treatment.asp

 आम प्रयोग होने वाली होम्योपैथिक औषधियाँ : लक्षण के अनुसार : [ मार्गेट टायेलेर की Pointers to the common Remedies देखें । ]

Aconite

Belladona

arsenic

Baptisia

Gelsemium

Eup Perf

Pyrogen

Bryonia

Rhus Tox

Mercurious

Camphor

Nux vom

AFTER INFLUENZA BADLY RECOVERED FROM

sulphur

china

arsenic

Cyprepedium pubescens

cyprepedin

Scutellaria lat

  • "genus epidemicus

[ चित्र को सफ़ और बडे आकार मे देखने के लिये किल्क करें ]

साभार : www.moleculardyne.com

माहामारियों मे दवा का चुनाव अन्य चुनाव की अपेक्षा आसान हो जाता है क्योंकि रोग के लक्षण लगभग एक से ही रह्ते हैं । और दवा का चुनाव  मुख्यत: एक या दो दवाओं पर आ टिकता  है ।  ऐसी अवस्था मे चयनित दवा को "genus epidemicus” कहते हैं । यही वजह थी कि 1918  के फ़्लू माहामारी मे होम्योपैथिक दवाओं से लाभ होने की संख्या अन्य पद्दतियों  की अपेक्षा कही अधिक थी ।

The indicated remedy in pandemics is usually very consistent and called the "genus epidemicus". This is narrowed down to a shortlist of three or less.

लेकिन क्या इन्फ़्लूजिनियम को "genus epidemicus” की श्रेणी मे डालना उचित है । हैनिमैन मुख्यत: इस तरह के चुनाव के पक्ष मे नही थे , कारण भले ही रोग का कारक एक ही हो लेकिन हर रोगी अपनी चारित्रिक विशेषताओं के होते हुये हर से भिन्न ही रहता है । "genus epidemicus” को लेकर हैनिमैन ने आर्गेनान मे कुछ विशेष निर्देश दिये हैं :

As per the guidelines laid down by Dr. Samuel Hahnemann in the Organon a Genus epidemics has to be found out in the specific area and it could be the best to be found out in the specific area and it could be the best prophylactic remedy.

    Source: ORGANON OF MEDICINE Aphorism 100-102

    § 100

    In investigating the totality of the symptoms of epidemic and sporadic diseases it is quite immaterial whether or not something similar has ever appeared in the world before under the same or any other name. The novelty or peculiarity of a disease of that kind makes no difference either in the mode of examining or of treating it, as the physician must any way regard to pure picture of every prevailing disease as if it were something new and unknown, and investigate it thoroughly for itself, if he desire to practice medicine in a real and radical manner, never substituting conjecture for actual observation, never taking for granted that the case of disease before him is already wholly or partially known, but always carefully examining it in all its phases; and this mode of procedure is all the more requisite in such cases, as a careful examination will show that every prevailing disease is in many respects a phenomenon of a unique character, differing vastly from all previous epidemics, to which certain names have been falsely applied – with the exception of those epidemics resulting from a contagious principle that always remains the same, such as smallpox, measles, etc.

    § 101

    It may easily happen that in the first case of an epidemic disease that presents itself to the physician’s notice he does not at once obtain a knowledge of its complete picture, as it is only by a close observation of several cases of every such collective disease that he can become conversant with the totality of its signs and symptoms. The carefully observing physician can, however, from the examination of even the first and second patients, often arrive so nearly at a knowledge of the true state as to have in his mind a characteristic portrait of it, and even to succeed in finding a suitable, homœopathically adapted remedy for it.

    § 102

    In the course of writing down the symptoms of several cases of this kind the sketch of the disease picture becomes ever more and more complete, not more spun out and verbose, but more significant (more characteristic), and including more of the peculiarities of this collective disease; on the one hand, the general symptoms (e.g., loss of appetite, sleeplessness, etc.) become precisely defined as to their peculiarities; and on the other, the more marked and special symptoms which are peculiar to but few diseases and of rarer occurrence, at least in the same combination, become prominent and constitute what is characteristic of this malady.1 All those affected with the disease prevailing at a given time have certainly contracted it from one and the same source and hence are suffering from the same disease; but the whole extent of such an epidemic disease and the totality of its symptoms (the knowledge whereof, which is essential for enabling us to choose the most suitable homœopathic remedy for this array of symptoms, is obtained by a complete survey of the morbid picture) cannot be learned from one single patient, but is only to be perfectly deduced (abstracted) and ascertained from the sufferings of several patients of different constitutions.

    1 The physician who has already, in the first cases, been able to choose a remedy approximating to the homœopathic specific, will, from the subsequence cases, be enabled either to verify the suitableness of the medicine chosen, or to discover a more appropriate, the most appropriate homœopathic remedy.

Homeopathic Individualized Q-potencies versus Fluoxetine for Moderate to Severe Depression: Double-blind, Randomized Non-inferiority Trial

Thursday, 20 August 2009

Homeopathic Individualized Q-potencies versus Fluoxetine for
Moderate to Severe Depression: Double-blind, Randomized
Non-inferiority Trial

U. C. Adler, N. M. P. Paiva, A. T. Cesar, M. S. Adler, A. Molina, A. E. Padula
and H. M. Calil
Faculdade de Medicina de Jundiaı ´, Homeopathy Graduation Programme, Department of Psychobiology,
Universidade Federal de Sa ˜ o Paulo, Sa ˜ o Paulo, Brazi

Homeopathy is a complementary and integrative medicine used in depression, The aim of this study is to investigate the non-inferiority and tolerability of individualized homeopathic medicines [Quinquagintamillesmial (Q-potencies)] in acute depression, using fluoxetine as active control. Ninety-one outpatients with moderate to severe depression were assigned to receive an individualized homeopathic medicine or fluoxetine 20mg day–1(up to 40mg day–1) in a pro-
spective, randomized, double-blind double-dummy 8-week, single-center trial. Primary efficacy measure was the analysis of the mean change in the Montgomery & Asberg Depression Rating  Scale (MADRS) depression scores, using a non-inferiority test with margin of 1.45. Secondary  efficacy outcomes were response and remission rates. Tolerability was assessed with the side
effect rating scale of the Scandinavian Society of Psychopharmacology. Mean MADRS scores  differences were not significant at the 4th (P¼0.654) and 8th weeks (P¼0.965) of treatment.  Non-inferiority of homeopathy was indicated because the upper limit of the confidence interval (CI) for mean difference in MADRS change was less than the non-inferiority margin: mean differences (homeopathy–fluoxetine) were 3.04 (95% CI 6.95, 0.86) and 2.4 (95% CI 6.05, 0.77) at 4th and 8th week, respectively. There were no significant differences between the percentages of response or remission rates in both groups. Tolerability: there were no significant differences between the side effects rates, although a higher percentage of patients treated with fluoxetine reported troublesome side effects and there was a trend toward greater
treatment interruption for adverse effects in the fluoxetine group. This study illustrates the feasibility of randomized controlled double-blind trials of homeopathy in depression and indicates the non-inferiority of individualized homeopathic Q-potencies as compared to fluoxetine in acute treatment of outpatients with moderate to severe depression.


Keywords: depression – drug therapy – fluoxetine – homeopathy – integrative and
alternative medicine – non-inferiority – Q-potencies – randomized controlled trial – remission –
response

Source :

               http://ecam.oxfordjournals.org/ 

               www.drptandon.blogspot.com 

Download :

                      Link 1

                      Link 2

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विश्व होम्योपैथी समुदाय ( Homeopathic World Community )

Friday, 29 May 2009

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चन्द  हफ्तों के अन्दर ही  विश्व  होम्योपैथी समुदाय का नेटवर्क दुनिया भर के ५४ देशों से ७५० होम्योपैथिक चिकित्सकों , छात्रों और होम्योपैथिक चिकित्सा पद्दति के प्रति रुझान रखने वालों के बीच लोकप्रिय हो चुका है । कम्यूनिटी का मुख्य उद्देशय होम्योपैथिक चिकित्सकों के बीच समन्वय और  सकारात्मक अनुभवों का आदान प्रदान करना है ।

होम्योपैथिक वर्ल्ड कम्यूनिटी मे शामिल होने केलिये http://www.homeopathyworldcommunity.com पर चटका लगायें ।

साभार : डॆबी ब्रुक





In six short weeks Homeopathy World Community Network has over 750 members representing 54 Countries around the world. Members are physicians and professional health providers who have years of training. Some are students presently taking degree programs at universities, colleges and certificate seminars around the world. Other members joined the movement to learn more after experiencing positive effects from homeopathy

Click HERE to join Homeopathic World Community

Courtesy : Debby Bruck

Dynamized Homeopathic Preparations in Cell Culture- a study report in Amala Cancer Research Centre, Kerala

Thursday, 28 May 2009

Courtesy : Oxford Journal

Although reports on the efficacy of homeopathic medicines in animal models are limited, there are even fewer reports on the in vitro action of these dynamized preparations. In Amla Cancer Research Centre, Kerala , Ellanzhiyil Surendran Sunila, Ramadasan Kuttan, Korengath Chandran Preethi and Girija Kuttan have evaluated the cytotoxic activity of 30C and 200C potencies of ten dynamized medicines against Dalton's Lymphoma Ascites, Ehrlich's Ascites Carcinoma, lung fibroblast (L929) and Chinese Hamster Ovary (CHO) cell lines and compared activity with their mother tinctures during short-term and long-term cell culture. The effect of dynamized medicines to induce apoptosis was also evaluated and they have studied how dynamized medicines affected genes expressed during apoptosis. Mother tinctures as well as some dynamized medicines showed significant cytotoxicity to cells during short and long-term incubation. Potentiated alcohol control did not produce any cytotoxicity at concentrations studied. The dynamized medicines were found to inhibit CHO cell colony formation and thymidine uptake in L929 cells and those of Thuja, Hydrastis and Carcinosinum were found to induce apoptosis in DLA cells. Moreover, dynamized Carcinosinum was found to induce the expression of p53 while dynamized Thuja produced characteristic laddering pattern in agarose gel electrophoresis of DNA. These results indicate that dynamized medicines possess cytotoxic as well as apoptosis-inducing properties.

Recently, limited investigations on the efficacy of dynamized medicines in animal models as well as clinical trials have reported that potentiated Lycopodium clavatum has protective action against CCl4-induced liver damage in rats (3) and that chelidonium 30C could ameliorate both p-dimethylaminoazobenzene and azodye-induced hepatocarcinogenesis in mice (4,5). Anti-genotoxic effect of different dynamized medicines has also been reported (6,7): Arsenicum album was found to ameliorate arsenic-induced toxicity in mice as well as in clinical studies and could reduce the elevated antinuclear antibody titer and hematological toxicities (8,9). Homeopathic therapy for asymptomatic HIV carriers has also proven beneficial (10) and recently Rajendran (11) reported homeopathy as a supportive therapy in cancer. Pathak et al. (12) investigated Ruta 6 on regression of human glioma brain cancer cell growth clinically and found that Ruta induces severe telomere erosion in MGRI brain cancer cells but has no effect on B-lymphoid cells and normal lymphocytes. Banerji and Banerji (13) reported that Ruta was effective for intracranial cysticercosis.

Very few investigations have explored the action of dynamized medicine in in vitro cell culture systems. Podophyllum has been shown to inhibit adhesion of neutrophils to serum-coated micro plates (14). Traumeen S, a homeopathic formulation used clinically to relieve trauma and inflammation has been shown to inhibit the production of Interleukin-β, TNF-{alpha} and Interleukin-8 by human T cells and monocytes in culture (15). Many homeopathic drugs at low potencies were found to potentiate oxidative metabolism in cultured cells (16).

Medicines Used :

From होम्योपैथी नई सोच/ नई दिशायें

Results:

Although the healing potential of homeopathic drugs is widely accepted, the exact mechanism of action is still unclear. In paragraphs 63–69 of Organon, Hahneman describes the mechanism of action through the ‘primary action’ of the medicine (dynamized or not) and the ‘secondary and curative reaction’ of the organism: ‘Every agent that acts upon the vitality, every medicine, deranges more or less the vital force, and causes a certain alteration in the health of the individual for a longer or a shorter period. This is termed primary action. Although a product of the medicinal and vital powers conjointly, it is principally due to the former power. To its action our vital force endeavors to oppose its own energy. This resistant action is a property, is indeed an automatic action of our life-preserving power, which goes by the name of secondary action or counteraction’. We have tried to explain the mechanism of action of the dynamized preparations taking into consideration the original proposition by Samuel Hahnemann and have approached this problem by investigating the action of dynamized drugs in various cultured cells in a systematic scientific manner.

Cytotoxic activity of a drug is often considered a first step towards elucidating its possible use against cancer and all of the drugs selected are being used by homeopathic practioners against cancer. They have  found that in short-term cytotoxicity research, some of the dynamized preparations showed significant cytotoxic actions against cancer cell lines and at times the activity was higher than that of the mother tinctures. For example, Conium at 200C potency was more cytotoxic than its mother tincture and that the cytotoxicity induced by Carcinosinum was higher at 200C than at 30C potency indicating that dynamization induces the cytotoxic potential of these medications. Results were more pronounced during MTT assay in which a longer period of incubation was involved. Many dynamized preparations at potency of 200C inhibited the growth of L929 cells. Clonogenic assay using CHO cells is a standard method to determine growth inhibitory activity of the drugs and we found that dynamized preparations of Thuja, Hydrastis, Carcinosinum and Podophyllum at 200C potency almost completely inhibited the CHO colony formation. As in other cases, Conium 200C was more active than 30C. We have confirmed the cytotoxic potential of dynamized preparations by thymidine uptake, for the marker of the inhibition DNA synthesis. As in the case other experiments, DNA synthesis was significantly inhibited by several dynamized preparations.

Cytotoxicity could be produced in cells either by necrosis or by apoptotic induction. Apoptosis, which is known as programmed cell death is highly regulated by events taking place within the cell and is highly relevant with respect to the destruction and removal of transformed cells from the body. The induction of apoptosis could be an external agent and a cascade of reactions taking place within the cell produces an ultimate cell death. Some of the events via occurring during apoptosis include morphological changes in the cell, production of apoptotic bodies, damage to genetic material and finally induction of proteolytic enzymes, which produces cellular destruction. Apoptosis could be visualized by morphology and DNA laddering. In the present study, dynamized preparations induced apoptosis as observed from their morphology and DNA laddering. Moreover, dynamized preparation of Carcinosinum could induce the p53, which is considered to be a proapoptotic protein and involved in signal transduction pathway.

The mechanism of action of some of the homeopathic drugs has been proposed. Potentiated preparation of Ruta possesses protective action on normal B-lymphoid cells against H2O2-induced chromosomal damage (13). Moreover, the telomere erosion was enhanced in cancer cells by treatment with Ruta while normal cells showed no change. Thus, the telomeres that protect individual chromosomes of cancer cells are damaged by Ruta, which may be the mechanism of its therapeutic action in brain cancer (13).

The protective effect of Chelidonium against p-DAB-induced hepatic cancer may occur by the modulating effect of the drug on restoration of damage caused to several gene-regulated phenomena like enzyme activities and chromosomal abnormalities. This gives insight into the mechanism of action, which may be by means of interfering with the process of carcinogenesis by actively modifying actions of oncogenes or by activating tumor suppressor genes (5). Another mechanism of actions of homeopathic drugs may occur through immune modification. Benveniste (17) has shown that human basophils undergo degranulation not only at usual anti-IgE antibody doses but also at extremely high dilutions. Bastide (18)has shown the therapeutic effect of high dilution of {alpha}–β interferon and thymic hormones on cellular immunity and had good therapeutic effect in immunodepressed patients. Similarly Bentwich et al. (19) revealed that small amounts of antigens are capable of specific antibody response. The role of immunity in the therapeutic efficacy of homeopathic medicines has also been reviewed (20).

There  results indicate that the dynamized preparation initially produces a secondary action on cells that is in line with the original proposition by Hahnemann on the mechanism of action of medicines dynamized or not. However, limited knowledge in this area does not fully explain the mechanism of action of all drugs . More scientific analyses are warranted to elucidate these interesting preparations of ultra dilutions.

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